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Genes that escape from X‐chromosome inactivation: Potential contributors to Klinefelter syndrome

One of the two X chromosomes in females is epigenetically inactivated, thereby compensating for the dosage difference in X‐linked genes between XX females and XY males. Not all X‐linked genes are completely inactivated, however, with 12% of genes escaping X chromosome inactivation and another 15% of...

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Bibliografske podrobnosti
izdano v:Am J Med Genet C Semin Med Genet
Main Authors: Navarro‐Cobos, Maria Jose, Balaton, Bradley P., Brown, Carolyn J.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7384012/
https://ncbi.nlm.nih.gov/pubmed/32441398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.c.31800
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