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Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements
BACKGROUND: X-chromosome inactivation (XCI) is a mechanism in which one of two X chromosomes in females is randomly inactivated in order to compensate for imbalance of gene dosage between sexes. However, about 15% of genes on the inactivated X chromosome (Xi) escape from XCI. The methylation level o...
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| Published in: | Clin Epigenetics |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8244138/ https://ncbi.nlm.nih.gov/pubmed/34193245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01121-6 |
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