Methylation status of genes escaping from X-chromosome inactivation in patients with X-chromosome rearrangements

BACKGROUND: X-chromosome inactivation (XCI) is a mechanism in which one of two X chromosomes in females is randomly inactivated in order to compensate for imbalance of gene dosage between sexes. However, about 15% of genes on the inactivated X chromosome (Xi) escape from XCI. The methylation level o...

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Dettagli Bibliografici
Pubblicato in:Clin Epigenetics
Autori principali: Kawashima, Sayaka, Hattori, Atsushi, Suzuki, Erina, Matsubara, Keiko, Toki, Machiko, Kosaki, Rika, Hasegawa, Yukihiro, Nakabayashi, Kazuhiko, Fukami, Maki, Kagami, Masayo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8244138/
https://ncbi.nlm.nih.gov/pubmed/34193245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01121-6
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