Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions

BACKGROUND: 5-Hydroxymethylcytosine (5hmC), converted from 5-methylcytosine (5mC) by ten-eleven translocation (Tet) enzymes, has recently drawn attention as the “sixth base” of DNA since it is considered an intermediate of the demethylation pathway. Nonetheless, it remains to be addressed how 5hmC i...

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Opis bibliograficzny
Wydane w:Clin Epigenetics
Główni autorzy: Matsubara, Keiko, Kagami, Masayo, Nakabayashi, Kazuhiko, Hata, Kenichiro, Fukami, Maki, Ogata, Tsutomu, Yamazawa, Kazuki
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2015
Hasła przedmiotowe:
Short Report
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552283/
https://ncbi.nlm.nih.gov/pubmed/26322139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0124-y
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