Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions

BACKGROUND: 5-Hydroxymethylcytosine (5hmC), converted from 5-methylcytosine (5mC) by ten-eleven translocation (Tet) enzymes, has recently drawn attention as the “sixth base” of DNA since it is considered an intermediate of the demethylation pathway. Nonetheless, it remains to be addressed how 5hmC i...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Matsubara, Keiko, Kagami, Masayo, Nakabayashi, Kazuhiko, Hata, Kenichiro, Fukami, Maki, Ogata, Tsutomu, Yamazawa, Kazuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552283/
https://ncbi.nlm.nih.gov/pubmed/26322139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0124-y
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