Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions

BACKGROUND: 5-Hydroxymethylcytosine (5hmC), converted from 5-methylcytosine (5mC) by ten-eleven translocation (Tet) enzymes, has recently drawn attention as the “sixth base” of DNA since it is considered an intermediate of the demethylation pathway. Nonetheless, it remains to be addressed how 5hmC i...

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Bibliografiset tiedot
Julkaisussa:Clin Epigenetics
Päätekijät: Matsubara, Keiko, Kagami, Masayo, Nakabayashi, Kazuhiko, Hata, Kenichiro, Fukami, Maki, Ogata, Tsutomu, Yamazawa, Kazuki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Short Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552283/
https://ncbi.nlm.nih.gov/pubmed/26322139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0124-y
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