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Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis
Phospholipidosis, the excessive accumulation of phospholipids within lysosomes, is a pathological response observed following exposure to many drugs across multiple therapeutic groups. A clear mechanistic understanding of the causes and implications of this form of drug toxicity has remained elusive...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8243516/ https://ncbi.nlm.nih.gov/pubmed/34087196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jlr.2021.100089 |
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