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Knockdown of Atg7 suppresses Tumorigenesis in a murine model of liver cancer

Hepatocellular Carcinoma (HCC) is the most common type of primary liver cancer in adults and a leading cause of cancer-related deaths worldwide. Studies have shown that autophagy is significantly involved in carcinogenesis, in particular, driven by activated RAS signaling. Autophagy related 7 (Atg7)...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Cho, Kyung Joo, Shin, Sun Yeong, Moon, Hyuk, Kim, Beom Kyung, Ro, Simon Weonsang
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8243000/
https://ncbi.nlm.nih.gov/pubmed/34174688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101158
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