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Structural mechanism of laminin recognition by integrin

Recognition of laminin by integrin receptors is central to the epithelial cell adhesion to basement membrane, but the structural background of this molecular interaction remained elusive. Here, we report the structures of the prototypic laminin receptor α6β1 integrin alone and in complex with three-...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Arimori, Takao, Miyazaki, Naoyuki, Mihara, Emiko, Takizawa, Mamoru, Taniguchi, Yukimasa, Cabañas, Carlos, Sekiguchi, Kiyotoshi, Takagi, Junichi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241838/
https://ncbi.nlm.nih.gov/pubmed/34188035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24184-8
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