Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process associated with low back pain (LBP). The pathogenesis is complicated, and the main pathological changes are IVD cell apoptosis and extracellular matrix (ECM) degradation. Apoptotic cell loss leads to ECM degradatio...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Med Sci
Autori principali: Zhang, Xiao-bo, Hu, Yi-cun, Cheng, Peng, Zhou, Hai-yu, Chen, Xiang-yi, Wu, Ding, Zhang, Rui-hao, Yu, De-chen, Gao, Xi-dan, Shi, Jin-tao, Zhang, Kai, Li, Shao-long, Song, Peng-jie, Wang, Ke-ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241771/
https://ncbi.nlm.nih.gov/pubmed/34220308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.59171
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