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Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process associated with low back pain (LBP). The pathogenesis is complicated, and the main pathological changes are IVD cell apoptosis and extracellular matrix (ECM) degradation. Apoptotic cell loss leads to ECM degradatio...

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Détails bibliographiques
Publié dans:Int J Med Sci
Auteurs principaux: Zhang, Xiao-bo, Hu, Yi-cun, Cheng, Peng, Zhou, Hai-yu, Chen, Xiang-yi, Wu, Ding, Zhang, Rui-hao, Yu, De-chen, Gao, Xi-dan, Shi, Jin-tao, Zhang, Kai, Li, Shao-long, Song, Peng-jie, Wang, Ke-ping
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241771/
https://ncbi.nlm.nih.gov/pubmed/34220308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.59171
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