Targeted therapy for intervertebral disc degeneration: inhibiting apoptosis is a promising treatment strategy

Intervertebral disc (IVD) degeneration (IDD) is a multifactorial pathological process associated with low back pain (LBP). The pathogenesis is complicated, and the main pathological changes are IVD cell apoptosis and extracellular matrix (ECM) degradation. Apoptotic cell loss leads to ECM degradatio...

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Detalhes bibliográficos
Publicado no:Int J Med Sci
Main Authors: Zhang, Xiao-bo, Hu, Yi-cun, Cheng, Peng, Zhou, Hai-yu, Chen, Xiang-yi, Wu, Ding, Zhang, Rui-hao, Yu, De-chen, Gao, Xi-dan, Shi, Jin-tao, Zhang, Kai, Li, Shao-long, Song, Peng-jie, Wang, Ke-ping
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241771/
https://ncbi.nlm.nih.gov/pubmed/34220308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.59171
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