Hexokinase 3 dysfunction promotes tumorigenesis and immune escape by upregulating monocyte/macrophage infiltration into the clear cell renal cell carcinoma microenvironment

Purpose: This study aimed to identify the potential prognostic role of HK3 and provide clues about glycolysis and the microenvironmental characteristics of ccRCC. Methods: Based on the Cancer Genome Atlas (TCGA, n = 533) and Gene expression omnibus (GEO) (n = 127) databases, real-world (n = 377) ccR...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Biol Sci
Auteurs principaux: Xu, Wenhao, Liu, Wang-Rui, Xu, Yue, Tian, Xi, Anwaier, Aihetaimujiang, Su, Jia-Qi, Zhu, Wen-Kai, Shi, Guo-Hai, Wei, Gao-Meng, Huang, Yong-Ping, Qu, Yuan-Yuan, Zhang, Hai-Liang, Ye, Ding-Wei
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2021
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241725/
https://ncbi.nlm.nih.gov/pubmed/34239350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.58295
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