Effective intraperitoneal gene transfection system using nanobubbles and ultrasound irradiation

In this study, we demonstrate the low toxicity and highly efficient and spatially improved transfection of plasmid DNA (pDNA) with liposomal nanobubbles (bubble liposomes [BLs]) using ultrasound (US) irradiation in mice. Naked pDNA with BLs was intraperitoneally injected, followed by US irradiation....

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Dades bibliogràfiques
Publicat a:Drug Deliv
Autors principals: Nishimura, Koyo, Fumoto, Shintaro, Fuchigami, Yuki, Hagimori, Masayori, Maruyama, Kazuo, Kawakami, Shigeru
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241157/
https://ncbi.nlm.nih.gov/pubmed/28446052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1319433
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