Lipid-based nanosystem of edaravone: development, optimization, characterization and in vitro/in vivo evaluation

Edaravone (EDR) is a well-recognized lipophilic free radical scavenger for diseases including neurodegenerative disease, cardiovascular disease, and cancer. However, its oral use is restricted due to poor oral bioavailability (BA). The aim of present research was to enable its oral use by developing...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Parikh, Ankit, Kathawala, Krishna, Tan, Chun Chuan, Garg, Sanjay, Zhou, Xin-Fu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8241028/
https://ncbi.nlm.nih.gov/pubmed/28633547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1337825
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