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WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation

Mutations in the WDR62 gene cause primary microcephaly, a pathological condition often associated with defective cell division that results in severe brain developmental defects. The precise function and localization of WDR62 within the mitotic spindle is, however, still under debate, as it has been...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Biol
Hauptverfasser: Guerreiro, Amanda, De Sousa, Filipe, Liaudet, Nicolas, Ivanova, Daria, Eskat, Anja, Meraldi, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: Rockefeller University Press 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240857/
https://ncbi.nlm.nih.gov/pubmed/34137788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202007171
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