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The long journey to bring a Myc inhibitor to the clinic

The oncogene Myc is deregulated in the majority of human tumors and drives numerous hallmarks of cancer. Despite its indisputable role in cancer development and maintenance, Myc is still undrugged. Developing a clinical inhibitor for Myc has been particularly challenging owing to its intrinsically d...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Whitfield, Jonathan R., Soucek, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240852/
https://ncbi.nlm.nih.gov/pubmed/34160558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202103090
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