Antiretroviral Tenofovir Induces Senescence-Associated β-Galactosidase Activity in Primary Human Brain Vascular Cells in Multi-Layer Three-Dimensional Co-Culture

Introduction In the current context of early diagnosis of HIV infection, immediate initiation of antiretroviral (ARV) therapy, and lifelong chronic treatment, the potential ARV toxicity is of particular concern. Emtricitabine (FTC) and tenofovir (TFV) are commonly used as backbone drugs in ARV regim...

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Vydáno v:Cureus
Hlavní autoři: Chang, Rachel C, Soontornniyomkij, Benchawanna, Umlauf, Anya, Soontornniyomkij, Virawudh
Médium: Artigo
Jazyk:Inglês
Vydáno: Cureus 2021
Témata:
Neurology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240677/
https://ncbi.nlm.nih.gov/pubmed/34235009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.15327
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