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Antiretroviral Tenofovir Induces Senescence-Associated β-Galactosidase Activity in Primary Human Brain Vascular Cells in Multi-Layer Three-Dimensional Co-Culture

Introduction In the current context of early diagnosis of HIV infection, immediate initiation of antiretroviral (ARV) therapy, and lifelong chronic treatment, the potential ARV toxicity is of particular concern. Emtricitabine (FTC) and tenofovir (TFV) are commonly used as backbone drugs in ARV regim...

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Библиографические подробности
Опубликовано в: :Cureus
Главные авторы: Chang, Rachel C, Soontornniyomkij, Benchawanna, Umlauf, Anya, Soontornniyomkij, Virawudh
Формат: Artigo
Язык:Inglês
Опубликовано: Cureus 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240677/
https://ncbi.nlm.nih.gov/pubmed/34235009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.15327
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