Antiretroviral Tenofovir Induces Senescence-Associated β-Galactosidase Activity in Primary Human Brain Vascular Cells in Multi-Layer Three-Dimensional Co-Culture

Introduction In the current context of early diagnosis of HIV infection, immediate initiation of antiretroviral (ARV) therapy, and lifelong chronic treatment, the potential ARV toxicity is of particular concern. Emtricitabine (FTC) and tenofovir (TFV) are commonly used as backbone drugs in ARV regim...

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Detalhes bibliográficos
Publicado no:Cureus
Main Authors: Chang, Rachel C, Soontornniyomkij, Benchawanna, Umlauf, Anya, Soontornniyomkij, Virawudh
Formato: Artigo
Idioma:Inglês
Publicado em: Cureus 2021
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240677/
https://ncbi.nlm.nih.gov/pubmed/34235009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.15327
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