Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination

BACKGROUND: Development of an effective vaccine against the pathogenic blood-stage infection of human malaria has proved challenging, and no candidate vaccine has affected blood-stage parasitemia following controlled human malaria infection (CHMI) with blood-stage Plasmodium falciparum. METHODS: We...

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Publicado no:Med (N Y)
Main Authors: Minassian, Angela M., Silk, Sarah E., Barrett, Jordan R., Nielsen, Carolyn M., Miura, Kazutoyo, Diouf, Ababacar, Loos, Carolin, Fallon, Jonathan K., Michell, Ashlin R., White, Michael T., Edwards, Nick J., Poulton, Ian D., Mitton, Celia H., Payne, Ruth O., Marks, Michael, Maxwell-Scott, Hector, Querol-Rubiera, Antonio, Bisnauthsing, Karen, Batra, Rahul, Ogrina, Tatiana, Brendish, Nathan J., Themistocleous, Yrene, Rawlinson, Thomas A., Ellis, Katherine J., Quinkert, Doris, Baker, Megan, Lopez Ramon, Raquel, Ramos Lopez, Fernando, Barfod, Lea, Folegatti, Pedro M., Silman, Daniel, Datoo, Mehreen, Taylor, Iona J., Jin, Jing, Pulido, David, Douglas, Alexander D., de Jongh, Willem A., Smith, Robert, Berrie, Eleanor, Noe, Amy R., Diggs, Carter L., Soisson, Lorraine A., Ashfield, Rebecca, Faust, Saul N., Goodman, Anna L., Lawrie, Alison M., Nugent, Fay L., Alter, Galit, Long, Carole A., Draper, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Clinical Advances
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240500/
https://ncbi.nlm.nih.gov/pubmed/34223402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medj.2021.03.014
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