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Yeast DNA polymerase η possesses two PIP-like motifs that bind PCNA and Rad6-Rad18 with different specificities

In translesion synthesis (TLS), specialized DNA polymerases, such as polymerase (pol) η and Rev1, are recruited to stalled replication forks. These polymerases form a multi-protein complex with PCNA, Rad6-Rad18, and other specialized polymerases. Pol η interacts with PCNA and Rev1 via a PCNA-interac...

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Publicado en:DNA Repair (Amst)
Autores principales: Ripley, Brittany M., Reusch, Devin T., Washington, M. Todd
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240473/
https://ncbi.nlm.nih.gov/pubmed/32932109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102968
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