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Immune Suppression of Glia Maturation Factor Reverses Behavioral Impairment, Attenuates Amyloid Plaque Pathology and Neuroinflammation in an Alzheimer’s disease Mouse Model

Alzheimer’s disease (AD) is an irreversible progressive neurodegenerative disorder recognized by accumulation of amyloid-plaques (APs) and neurofibrillary tangles (NFTs) and eventually loss of memory. Glia maturation factor (GMF), a neuroinflammatory protein first time isolated and cloned in our lab...

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Detalhes bibliográficos
Publicado no:J Neuroimmune Pharmacol
Main Authors: Ahmed, Mohammad Ejaz, Selvakumar, Govindhasamy Pushpavathi, Thangavel, Ramasamy, Kempuraj, Duraisamy, Raikwar, Sudhanshu P., Zaheer, Smita, Iyer, Shankar, Zaheer, Asgar
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240471/
https://ncbi.nlm.nih.gov/pubmed/32504312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-020-09929-4
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