Immune Suppression of Glia Maturation Factor Reverses Behavioral Impairment, Attenuates Amyloid Plaque Pathology and Neuroinflammation in an Alzheimer’s disease Mouse Model

Alzheimer’s disease (AD) is an irreversible progressive neurodegenerative disorder recognized by accumulation of amyloid-plaques (APs) and neurofibrillary tangles (NFTs) and eventually loss of memory. Glia maturation factor (GMF), a neuroinflammatory protein first time isolated and cloned in our lab...

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Pubblicato in:J Neuroimmune Pharmacol
Autori principali: Ahmed, Mohammad Ejaz, Selvakumar, Govindhasamy Pushpavathi, Thangavel, Ramasamy, Kempuraj, Duraisamy, Raikwar, Sudhanshu P., Zaheer, Smita, Iyer, Shankar, Zaheer, Asgar
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240471/
https://ncbi.nlm.nih.gov/pubmed/32504312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-020-09929-4
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