Targeted Gene Editing of Glia Maturation Factor in Microglia: A Novel Alzheimer’s Disease Therapeutic Target

Alzheimer’s disease (AD) is a devastating, progressive neurodegenerative disorder that leads to severe cognitive impairment in elderly patients. Chronic neuroinflammation plays an important role in the AD pathogenesis. Glia maturation factor (GMF), a proinflammatory molecule discovered in our labora...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Raikwar, Sudhanshu P., Thangavel, Ramasamy, Dubova, Iuliia, Selvakumar, Govindhasamy Pushpavathi, Ahmed, Mohammad Ejaz, Kempuraj, Duraisamy, Zaheer, Smita, Iyer, Shankar, Zaheer, Asgar
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6344368/
https://ncbi.nlm.nih.gov/pubmed/29704201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1068-y
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