CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells

Microglial cells are brain specific professional phagocytic immune cells that play a crucial role in the inflammation-mediated neurodegeneration especially in Parkinson’s disease (PD) and Alzheimer’s disease. Glia maturation factor (GMF) is a neuroinflammatory protein abundantly expressed in the bra...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neuroimmune Pharmacol
Egile Nagusiak: Selvakumar, Govindhasamy Pushpavathi, Ahmed, Mohammad Ejaz, Raikwar, Sudhanshu P., Thangavel, Ramasamy, Kempuraj, Duraisamy, Dubova, Iuliia, Saeed, Daniyal, Zahoor, Haris, Premkumar, Keerthivaas, Zaheer, Smita, Iyer, Shankar, Zaheer, Asgar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711834/
https://ncbi.nlm.nih.gov/pubmed/30810907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11481-019-09833-6
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