DNA methylation in the OPG/RANK/RANKL pathway is associated with steroid-induced osteonecrosis of the femoral head

BACKGROUND: Dysregulation of the OPG/RANK/RANKL signalling pathway is a key step in the occurrence of steroid-induced osteonecrosis of the femoral head (ONFH). This study aims to understand the degree of methylation of the OPG, RANK, and RANKL genes in steroid-related ONFH. METHODS: A case-control s...

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Vydáno v:BMC Musculoskelet Disord
Hlavní autoři: Sun, Menghu, Cao, Yuju, Yang, Xiaolong, An, Feimeng, Wu, Huiqiang, Wang, Jianzhong
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240366/
https://ncbi.nlm.nih.gov/pubmed/34187427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-021-04472-6
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