IL-15 deficiency alleviates steroid-induced osteonecrosis of the femoral head by impact osteoclasts via RANKL-RANK-OPG system

BACKGROUND: Whether IL-15 is involved in the development of steroid-induced osteonecrosis of the femoral head (ONFH) is investigated. METHODS: C57BL/6 J and l15(−/−)mice were injected with methylprednisolone to induce wide type osteonecrosis (WT ON) and IL-15 deficiency osteonecrosis (IL-15(−/−) ON)...

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Bibliografski detalji
Izdano u:Immun Ageing
Glavni autori: Zhou, Zubin, Lin, Yiwei, Pan, Chenhao, Wang, Nan, Zhou, Lihui, Shan, Haojie, Gao, Youshui, Yu, Xiaowei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7291529/
https://ncbi.nlm.nih.gov/pubmed/32536957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-020-00190-0
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