Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA): A Randomized Clinical Trial

IMPORTANCE: In 2019, the US Food and Drug Administration (FDA) received a citizen petition indicating that ranitidine contained the probable human carcinogen N-nitrosodimethylamine (NDMA). In addition, the petitioner proposed that ranitidine could convert to NDMA in humans; however, this was primari...

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Detalhes bibliográficos
Publicado no:JAMA
Main Authors: Florian, Jeffry, Matta, Murali K., DePalma, Ryan, Gershuny, Victoria, Patel, Vikram, Hsiao, Cheng-Hui, Zusterzeel, Robbert, Rouse, Rodney, Prentice, Kristin, Nalepinski, Colleen Gosa, Kim, Insook, Yi, Sojeong, Zhao, Liang, Yoon, Miyoung, Selaya, Susan, Keire, David, Korvick, Joyce, Strauss, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8240005/
https://ncbi.nlm.nih.gov/pubmed/34180947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2021.9199
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