Molecular chaperone RAP interacts with LRP1 in a dynamic bivalent mode and enhances folding of ligand-binding regions of other LDLR family receptors

The low-density lipoprotein receptor (LDLR) family of receptors are cell-surface receptors that internalize numerous ligands and play crucial role in various processes, such as lipoprotein metabolism, hemostasis, fetal development, etc. Previously, receptor-associated protein (RAP) was described as...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Marakasova, Ekaterina, Olivares, Philip, Karnaukhova, Elena, Chun, Haarin, Hernandez, Nancy E., Kurasawa, James H., Hassink, Gabriela U., Shestopal, Svetlana A., Strickland, Dudley K., Sarafanov, Andrey G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8239462/
https://ncbi.nlm.nih.gov/pubmed/34058195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100842
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