Mapping the Binding Region on the Low Density Lipoprotein Receptor for Blood Coagulation Factor VIII

Low density lipoprotein receptor (LDLR) was shown to mediate clearance of blood coagulation factor VIII (FVIII) from the circulation. To elucidate the mechanism of interaction of LDLR and FVIII, our objective was to identify the region of the receptor necessary for binding FVIII. Using surface plasm...

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Detalhes bibliográficos
Main Authors: Kurasawa, James H., Shestopal, Svetlana A., Karnaukhova, Elena, Struble, Evi B., Lee, Timothy K., Sarafanov, Andrey G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724656/
https://ncbi.nlm.nih.gov/pubmed/23754288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.468108
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