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Activation of natural killer T cells enhances the function of regulatory T-cell therapy in suppressing murine GVHD

Cellular therapy with regulatory T cells (Tregs) has shown promising results for suppressing graft-versus-host disease (GVHD) while preserving graft vs tumor effects in animal models and phase 1/2 clinical trials. However, a paucity of Tregs in the peripheral blood makes it difficult to acquire suff...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Hirai, Toshihito, Lin, Po-Yu, Simonetta, Federico, Maas-Bauer, Kristina, Turkoz, Mustafa, Mavers, Melissa, Baker, Jeanette, Negrin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238485/
https://ncbi.nlm.nih.gov/pubmed/34100904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003272
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