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Turning enemies into allies—reprogramming tumor-associated macrophages for cancer therapy

Checkpoint blockade therapies that target inhibitory receptors on T cells have revolutionized clinical oncology. Antibodies targeting CTLA-4 or the PD-1/PD-L1 axis are now successfully used alone or in combination with chemotherapy for numerous tumor types. Despite the clinical success of checkpoint...

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Bibliografiske detaljer
Udgivet i:Med (N Y)
Main Authors: Molgora, Martina, Colonna, Marco
Format: Artigo
Sprog:Inglês
Udgivet: 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238417/
https://ncbi.nlm.nih.gov/pubmed/34189494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.medj.2021.05.001
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