Loss of SNAI2 in Prostate Cancer Correlates With Clinical Response to Androgen Deprivation Therapy

PURPOSE: Androgen receptor (AR) signaling is important in prostate cancer progression, and therapies that target this pathway have been the mainstay of treatment for advanced disease for over 70 years. Tumors eventually progress despite castration through a number of well-characterized mechanisms; h...

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Bibliographic Details
Published in:JCO Precis Oncol
Main Authors: Cmero, Marek, Kurganovs, Natalie J., Stuchbery, Ryan, McCoy, Patrick, Grima, Corrina, Ngyuen, Anne, Chow, Ken, Mangiola, Stefano, Macintyre, Geoff, Howard, Nicholas, Kerger, Michael, Dundee, Philip, Ruljancich, Paul, Clarke, David, Grummet, Jeremy, Peters, Justin S., Costello, Anthony J., Norden, Sam, Ryan, Andrew, Parente, Phillip, Hovens, Christopher M., Corcoran, Niall M.
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Health 2021
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ORIGINAL REPORTS
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238292/
https://ncbi.nlm.nih.gov/pubmed/34322653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/PO.20.00337
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