Pharmacokinetics of tenofovir alafenamide with and without cobicistat in pregnant and postpartum women living with HIV: Results from IMPAACT P1026s

OBJECTIVE: To evaluate the pharmacokinetics of tenofovir alafenamide (TAF) 10 mg with cobicistat and 25 mg without boosting in pregnant and postpartum women with HIV and to characterize TAF placental transfer and infant washout pharmacokinetics. DESIGN: Open-label, multicenter phase IV prospective s...

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Publicado no:AIDS
Main Authors: BROOKS, Kristina M., MOMPER, Jeremiah D., PINILLA, Mauricio, STEK, Alice M., BARR, Emily, WEINBERG, Adriana, DEVILLE, Jaime G., FEBO, Irma L., CIELO, Mikhaela, GEORGE, Kathleen, DENSON, Kayla, RUNGRUENGTHANAKIT, Kittipong, SHAPIRO, David E., SMITH, Elizabeth, CHAKHTOURA, Nahida, ROONEY, James F., HAUBRICH, Richard, ESPINA, Rowena, CAPPARELLI, Edmund V., MIROCHNICK, Mark, BEST, Brookie M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238253/
https://ncbi.nlm.nih.gov/pubmed/33252495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000002767
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