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TERT and its binding protein: overexpression of GABPA/B in high grade gliomas
Enhanced expression of TERT in gliomas is a result of two hotspot mutations, C228T and C250T, at the promoter region. GA-binding proteins selectively bind at these positions, respectively, causing an activation of the promoter and overexpression of TERT. GABP is a multimeric protein consisting of GA...
Gorde:
| Argitaratua izan da: | Oncotarget |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Impact Journals LLC
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8238242/ https://ncbi.nlm.nih.gov/pubmed/34194624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27985 |
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