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P04.68 Relation of the expression between TERT and GABPA/B isoforms in gliomas using quantitative real time-PCR
BACKGROUND: Enhanced expression of TERT in gliomas is a result of two hotspot mutations, C228T and C250T, at the promoter region. The GABP of the ETS family selectively binds at these positions respectively causing an activation of the promoter and overexpression of TERT. GABP is a heterotetrameric...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144560/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy139.302 |
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