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Hydroxychloroquine (HCQ) decreases the benefit of anti-PD-1 immune checkpoint blockade in tumor immunotherapy

Immunotherapy using checkpoint blockade (ICB) with antibodies such as anti-PD-1 has revolutionised the treatment of many cancers. Despite its use to treat COVID-19 patients and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis, the effect of hydroxychloroquine (HCQ) o...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Krueger, Janna, Santinon, Francois, Kazanova, Alexandra, Issa, Mark E., Larrivee, Bruno, Kremer, Richard, Milhalcioiu, Catalin, Rudd, Christopher E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238207/
https://ncbi.nlm.nih.gov/pubmed/34181666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251731
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