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Application of ultrasound elastography for monitoring the effects of TβR1 shRNA therapy on hepatic fibrosis in a rat model

BACKGROUND: To investigate the application of ultrasound elastography in monitoring the effects of the transforming growth factor (TGF)-β1 signaling pathway-targeted combination therapy for hepatic fibrosis. METHODS: 1. Short hairpin RNA (shRNA) constructs targeted towards TβR1 were designed, synthe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shi, Xiangzhou, Li, Jinghua, Min, Binying, Yang, Ruijing, He, Chunxiang, Yang, Yilin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8238185/
https://ncbi.nlm.nih.gov/pubmed/34181670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0253150
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