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Host immunity following near-infrared photoimmunotherapy is enhanced with PD-1 checkpoint blockade to eradicate established antigenic tumors

Near-infrared photoimmunotherapy (NIR-PIT) induces immunogenic cell death, but has mostly failed to induce durable antitumor responses in syngenic tumor mouse models. We hypothesized that adaptive immune resistance could be limiting durable responses after treatmemt with NIR-PIT. We investigated the...

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Détails bibliographiques
Publié dans:Cancer Immunol Res
Auteurs principaux: Nagaya, Tadanobu, Friedman, Jay, Maruoka, Yasuhiro, Ogata, Fusa, Okuyama, Shuhei, Clavijo, Paul E., Choyke, Peter L., Allen, Clint, Kobayashi, Hisataka
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237708/
https://ncbi.nlm.nih.gov/pubmed/30683733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0546
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