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Revisiting the consequences of deleting the X inactivation center

Mammalian cells equalize X-linked dosages between the male (XY) and female (XX) sexes by silencing one X chromosome in the female sex. This process, known as “X chromosome inactivation” (XCI), requires a master switch within the X inactivation center (Xic). The Xic spans several hundred kilobases in...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Yin, Hao, Wei, Chunyao, Lee, Jeannie T.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237661/
https://ncbi.nlm.nih.gov/pubmed/34161282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2102683118
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