Fever supports CD8(+) effector T cell responses by promoting mitochondrial translation

Fever can provide a survival advantage during infection. Metabolic processes are sensitive to environmental conditions, but the effect of fever on T cell metabolism is not well characterized. We show that in activated CD8(+) T cells, exposure to febrile temperature (39 °C) augmented metabolic activi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: O’Sullivan, David, Stanczak, Michal A., Villa, Matteo, Uhl, Franziska M., Corrado, Mauro, Klein Geltink, Ramon I., Sanin, David E., Apostolova, Petya, Rana, Nisha, Edwards-Hicks, Joy, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan L., Fabri, Mario, Curtis, Jonathan D., Buck, Michael D., Patterson, Annette E., Regina, Annamaria, Field, Cameron S., Baixauli, Francesc, Puleston, Daniel J., Pearce, Edward J., Zeiser, Robert, Pearce, Erika L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2021
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237659/
https://ncbi.nlm.nih.gov/pubmed/34161266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023752118
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk