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Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling
Skeletal fragility in the elderly does not simply result from a loss of bone mass. However, the mechanisms underlying the concurrent decline in bone mass, quality, and mechanosensitivity with age remain unclear. The important role of osteocytes in these processes and the age-related degeneration of...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8237574/ https://ncbi.nlm.nih.gov/pubmed/34161267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2023999118 |
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