Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T(4)) have a higher incidence of NAFLD, and thyroid hormone treatment is very...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Bruinstroop, Eveline, Zhou, Jin, Tripathi, Madhulika, Yau, Winifred W., Boelen, Anita, Singh, Brijesh Kumar, Yen, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237360/
https://ncbi.nlm.nih.gov/pubmed/34098145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101266
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