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HBV Integration Induces Complex Interactions between Host and Viral Genomic Functions at the Insertion Site

Hepatitis B virus (HBV), one of the well-known DNA oncogenic viruses, is the leading cause of hepatocellular carcinoma (HCC). In infected hepatocytes, HBV DNA can be integrated into the host genome through an insertional mutagenesis process inducing tumorigenesis. Dissection of the genomic features...

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Bibliografiske detaljer
Udgivet i:J Clin Transl Hepatol
Main Authors: Zhang, Dake, Zhang, Ke, Protzer, Urlike, Zeng, Changqing
Format: Artigo
Sprog:Inglês
Udgivet: XIA & HE Publishing Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237140/
https://ncbi.nlm.nih.gov/pubmed/34221926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14218/JCTH.2021.00062
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