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Peanut protein acts as a Th2 adjuvant by inducing RALDH2 in human antigen-presenting cells

BACKGROUND: Peanut is a potent inducer of pro-allergenic Th2 responses in susceptible individuals. Antigen-presenting cells (APC) including dendritic cells and monocytes instruct naïve T cells to differentiate into various effector cells, determining immune responses such as allergy and tolerance. O...

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Bibliografiske detaljer
Udgivet i:J Allergy Clin Immunol
Main Authors: Ruiter, Bert, Smith, Neal P., Fleming, Elizabeth, Patil, Sarita U., Hurlburt, Barry K., Maleki, Soheila J., Shreffler, Wayne G.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8236067/
https://ncbi.nlm.nih.gov/pubmed/33378690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.11.047
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