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Tumor Microenvironment-Responsive Shell/Core Composite Nanoparticles for Enhanced Stability and Antitumor Efficiency Based on a pH-Triggered Charge-Reversal Mechanism

High systemic stability and effective tumor accumulation of chemotherapeutic agents are indispensable elements that determine their antitumor efficacy. PEGylation of nanoparticles (NPs) could prolong the retention time in vivo by improving their stability in circulation, but treatment suffers reduce...

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Publicat a:Pharmaceutics
Autors principals: Luo, Qiuhua, Shi, Wen, Wang, Puxiu, Zhang, Yu, Meng, Jia, Zhang, Ling
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235205/
https://ncbi.nlm.nih.gov/pubmed/34208641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060895
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