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Tumor Microenvironment-Responsive Shell/Core Composite Nanoparticles for Enhanced Stability and Antitumor Efficiency Based on a pH-Triggered Charge-Reversal Mechanism

High systemic stability and effective tumor accumulation of chemotherapeutic agents are indispensable elements that determine their antitumor efficacy. PEGylation of nanoparticles (NPs) could prolong the retention time in vivo by improving their stability in circulation, but treatment suffers reduce...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Luo, Qiuhua, Shi, Wen, Wang, Puxiu, Zhang, Yu, Meng, Jia, Zhang, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235205/
https://ncbi.nlm.nih.gov/pubmed/34208641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060895
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