LRP5 Regulates HIF-1α Stability via Interaction with PHD2 in Ischemic Myocardium

Low-density lipoprotein receptor-related protein 5 (LRP5) has been studied as a co-receptor for Wnt/β-catenin signaling. However, its role in the ischemic myocardium is largely unknown. Here, we show that LRP5 may act as a negative regulator of ischemic heart injury via its interaction with prolyl h...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Ju, Sujin, Lim, Leejin, Wi, Kwanhwan, Park, Changwon, Ki, Young-Jae, Choi, Dong-Hyun, Song, Heesang
Format: Artigo
Language:Inglês
Published: MDPI 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235097/
https://ncbi.nlm.nih.gov/pubmed/34205318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126581
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