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Distinct iNKT cell populations use IFNγ or ER stress-induced IL-10 to control adipose tissue homeostasis

Adipose tissue invariant natural killer T (iNKT) cells are phenotypically different from other iNKT cells because they produce IL-10 and control metabolic homeostasis. Why that is the case is unclear. Here, using single-cell RNA-sequencing we found several adipose iNKT clusters, which we grouped int...

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Podrobná bibliografie
Vydáno v:Cell Metab
Hlavní autoři: LaMarche, Nelson M., Kane, Harry, Kohlgruber, Ayano C., Dong, Han, Lynch, Lydia, Brenner, Michael B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234787/
https://ncbi.nlm.nih.gov/pubmed/32516575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.05.017
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