LABRAT reveals association of alternative polyadenylation with transcript localization, RNA binding protein expression, transcription speed, and cancer survival

BACKGROUND: The sequence content of the 3′ UTRs of many mRNA transcripts is regulated through alternative polyadenylation (APA). The study of this process using RNAseq data, though, has been historically challenging. RESULTS: To combat this problem, we developed LABRAT, an APA isoform quantification...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Genomics
Egile Nagusiak: Goering, Raeann, Engel, Krysta L., Gillen, Austin E., Fong, Nova, Bentley, David L., Taliaferro, J. Matthew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2021
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234626/
https://ncbi.nlm.nih.gov/pubmed/34174817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-021-07781-1
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