Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity

Inflammasomes are powerful cytosolic sensors of environmental stressors and are critical for triggering interleukin-1 (IL-1)-mediated inflammatory responses. However, dysregulation of inflammasome activation may lead to pathological conditions, and the identification of negative regulators for thera...

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Publicat a:Int J Mol Sci
Autors principals: Pariano, Marilena, Pieroni, Stefania, De Luca, Antonella, Iannitti, Rossana G., Borghi, Monica, Puccetti, Matteo, Giovagnoli, Stefano, Renga, Giorgia, D’Onofrio, Fiorella, Bellet, Marina M., Stincardini, Claudia, Della-Fazia, Maria Agnese, Servillo, Giuseppe, van de Veerdonk, Frank L., Costantini, Claudio, Romani, Luigina
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234597/
https://ncbi.nlm.nih.gov/pubmed/34207085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22126531
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