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Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy

The ability to regulate the recruitment of immune cells makes chemokines and their receptors attractive drug targets in many inflammatory diseases. Based on its preferential expression on T helper type 2 (Th2) cells, C-C chemokine receptor type 4 (CCR4) has been widely studied in the context of alle...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Bozza, Silvia, Iannitti, Rossana Giulietta, Pariano, Marilena, Renga, Giorgia, Costantini, Claudio, Romani, Luigina, Bayry, Jagadeesh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996545/
https://ncbi.nlm.nih.gov/pubmed/33669094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030351
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