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Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy

The ability to regulate the recruitment of immune cells makes chemokines and their receptors attractive drug targets in many inflammatory diseases. Based on its preferential expression on T helper type 2 (Th2) cells, C-C chemokine receptor type 4 (CCR4) has been widely studied in the context of alle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomolecules
Hauptverfasser: Bozza, Silvia, Iannitti, Rossana Giulietta, Pariano, Marilena, Renga, Giorgia, Costantini, Claudio, Romani, Luigina, Bayry, Jagadeesh
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996545/
https://ncbi.nlm.nih.gov/pubmed/33669094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030351
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