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Small Molecule CCR4 Antagonists Protect Mice from Aspergillus Infection and Allergy

The ability to regulate the recruitment of immune cells makes chemokines and their receptors attractive drug targets in many inflammatory diseases. Based on its preferential expression on T helper type 2 (Th2) cells, C-C chemokine receptor type 4 (CCR4) has been widely studied in the context of alle...

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Bibliografski detalji
Izdano u:Biomolecules
Glavni autori: Bozza, Silvia, Iannitti, Rossana Giulietta, Pariano, Marilena, Renga, Giorgia, Costantini, Claudio, Romani, Luigina, Bayry, Jagadeesh
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7996545/
https://ncbi.nlm.nih.gov/pubmed/33669094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11030351
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