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Balancing the CD38 Expression on Effector and Target Cells in Daratumumab-Mediated NK Cell ADCC against Multiple Myeloma

SIMPLE SUMMARY: We tracked the cytotoxic potential of NK cells towards multiple myeloma cells in daratumumab-mediated antibody-dependent cellular cytotoxicity assays. These cytotoxicity levels could be directly correlated to the expression of the target antigen (CD38) and to the percentage of fratri...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Lejeune, Margaux, Duray, Elodie, Peipp, Matthias, Clémenceau, Béatrice, Baron, Frédéric, Beguin, Yves, Caers, Jo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8234557/
https://ncbi.nlm.nih.gov/pubmed/34203012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13123072
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